| Lysine-specific histonedemethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch |
Hao Sun, Lining Liang1, Yuan Li, Chengqian Feng, Lingyu Li, Yixin Zhang, Songwei He,Duanqing Pei1, Yunqian Guo,Hui Zheng |
2016 Aug |
Scientific Reports |
| Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide |
Jian Wang, Shi Tang,Qiang Zhu |
2016 Jul |
Organic Letters |
| Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression |
Dongshan Yang, Jun Song, Jifeng Zhang, Jie Xu, Tianqing Zhu, Zhong Wang, Liangxue Lai,Y. Eugene Chen |
2016 Apr |
Scientific Reports |
| CRISPR/Cas9-mediated mutation of PHEX in rabbit recapitulates human X-linked hypophosphatemia (XLH) |
Tingting Sui1, Lin Yuan1, Huan Liu, Mao Chen, Jichao Deng, Yong Wang, Zhanjun Li, Liangxue Lai |
2016 Jul |
Human Molecular Genetics |
| CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts |
Lin Yuan, Tingting Sui, Mao Chen, Jichao Deng, Yongye Huang, Jian Zeng, Qingyan Lv, Yuning Song, Zhanjun Li,Liangxue Lai |
2016 Feb |
Scientific Reports |
| Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9 |
Qingyan Lv, Lin Yuan, Jichao Deng, Mao Chen, Yong Wang, Jian Zeng, Zhanjun Li,Liangxue Lai |
2016 Apr |
Scientific RepoRts |
| Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators |
Shu Wei, Qingjian Zou, Sisi Lai, Quanjun Zhang, Li Li, Quanmei Yan,Xiaoqing Zhou, Huilin Zhong， Liangxue Lai |
2016 Jan |
Scientific Reports |
| Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering |
Yi Yang, Kepin Wang, Han Wu, Qin Jin, Degong Ruan, Zhen Ouyang, Bentian Zhao, Zhaoming Liu, Yu Zhao, Quanjun Zhang, Nana Fan, Qishuai Liu, Shimei Guo，Lei Bu, Yong Fan, Xiaofang Sun, Xiaoping Li, Liangxue Lai |
2016 Apr |
Journal of Molecular Cell Biology |
| Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities |
Jinhong Bai, Chenzhong Liao,Yanghan Liu, Xiaochu Qin, Jiaxuan Chen, Yatao Qiu,Dongguang Qin, Zheng Li,Zheng-Chao Tu,Sheng Jiang |
2016 Jun |
Journal of Medicinal Chemistry |
| Pd-Catalyzed C(sp2)-H carbonylation of 2-benzylpyridines for the synthesis of pyridoisoquinolinones |
Zeqiang Xie, Shuang Luo,Qiang Zhu |
2016 Oct |
Chemical Communications |
| A metal-free synthesis of 2-aminobenzothiazoles through aminyl radical addition to aryl isothiocyanates |
Yimiao He, Jing Li, Shuang Luo, Jinbo Huang,Qiang Zhu |
2016 Jun |
Chemical Communications |
| Transcriptional Control of Somatic Cell Reprogramming |
Yan Xu, Meng Zhang, Wenjuan Li, Xihua Zhu, Xichen Bao, Baoming Qin, Andrew P. Hutchins, Miguel A. Esteban |
2016 Apr |
Trends in Cell Biology |
| Gadd45a is a heterochromatin relaxer that enhances iPS cell generation |
Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Sch？ler, Guoliang Xu, Xingguo Liu, Duanqing Pei |
2016 Nov |
EMBO Reports |
| Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis |
Ke Huang, Jiao Gao, Juan Du, Ning Ma, Yanling Zhu, Pengfei Wu,Tian Zhang,Wenqian Wang,Yuhang Li, Qianyu Chen, Andrew Paul Hutchins, Zhongzhou Yang, Yi Zheng,Jian Zhang, Yongli Shan, Xuejia Li, Baojian Liao, Jiajun Liu, Jinyong Wang, Bing Liu,Guangjin Pan |
2016 Nov |
Stem Cell Reports |
| Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors |
Zhen Wang, Huan Bian, Sergio G. Bartual, Wenting Du, Jinfeng Luo, Hu Zhao, Shasha Zhang, Cheng Mo, Yang Zhou, Yong Xu, Zhengchao Tu, Xiaomei Ren, Xiaoyun Lu, Rolf A. Brekken, Libo Yao, Alex N. Bullock, Jin Su, Ke Ding |
2016 Jun |
Journal of Medicinal Chemistry |
