1 Research Assistant (RA) Position Open Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou, China Pia Cosma Reprogramming and Regeneration Laboratory 1000 Talent awarded
The Guangzhou Institutes of Biomedicine and Health (GIBH, http://english.gibh.cas.cn/about/at/) is focused in research areas including stem cell and regenerative medicine, chemical biology, immunology and infectious diseases. Aimed to achieve the goal of "Healthy China" strategy and satisfy human health demands, GIBH is exploring disease mechanism with the cutting--‐edge technologies and developing innovative protocols for disease control and prevention. It provides excellent R&D platform in biomedicine and functions as an incubator for bioengineering and pharmaceutical industries to support local economic development as well as national strategic R&D programs. Reprogramming and Regeneration Laboratory
Pia Cosma’s group is an internationally recognized laboratory and will start at GIBH in August 2018. The group has as main objective to investigate the mechanisms controlling the reprogramming of somatic cells, and to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. Cosma’s group has discovered that activation of the Wnt/β--‐catenin signalling pathway enhances cell--‐fusion--‐mediated reprogramming of a variety of somatic cells and studied extensively the mechanism behind (Lluis et al., Cell Stem Cell 2008; Stem Cells 2010; PNAS
2011; Aulicino et al., Stem Cell Report 2014; Marucci et al. Cell Reports 2014; De Jaime--‐ Soguero et al. Plos Genetics 2017). Cosma’s group demonstrated that regeneration of the retina, dopaminergic neurons in Parkinson’s disease and of liver after hepatectomy is possible via Wnt controlled cell--‐fusion--‐mediated reprogramming (Sanges et al., Cell Reports
2013; J. of Clinical Investigation 2016; Pesaresi et al. eBioMedicine 2018; Altarche--‐Xifro’ et
al., eBioMedicine 2016; Pedone et al., Cell Reports 2017).
In addition, Cosma’s Group has a long interest in studying gene and chromatin function (Cantone et al, Cell 2009). Recently using super resolution microscopy (STORM), the group has identified a new model of chromatin fiber assembly and how the fiber changes in somatic and embryonic stem cells (Ricci et al. Cell 2015, Neguembor et al., NAR 2017).
Post Description and Candidate requirements
The Cosma group is looking for a highly motivated Research Assistant (RA) with previous expertise in biology, biomedicine or related disciplines. The candidate will ideally hold a PhD and will have some previous experience in cell and molecular biology and preferentially in in cell culture. He/she will be a lab manager dedicated part of the time to administrative duties, including organization for the best functioning of the laboratory, and part of the time he/she will be a technical assistant for research projects. The candidate will have a very good knowledge of English.
The offer is to cover a Research Assistant (RA) position with a competitive salary that
will be well matched relative to the cost of living in Guangzhou.
The job will start ideally as soon as the candidate is hired.
All applications must be addressed to Pia Cosma; and include a full CV with contact details, a cover motivation letter and contacts of 2--‐3 references. Please submit your application at: email@example.com
Deadline July 31 2018 (note that applications will be continually monitored and suitable
candidates will be hired as soon as they are identified)
pls send your CV to firstname.lastname@example.org