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发表日期:2018-06-07来源:放大 缩小

1 Research Assistant (RA) Position Open Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences Guangzhou, ChinPia Cosma Reprogramming and Regeneration Laborator1000 Talent awarded

The Guangzhou                                                 Institutes  of Biomedicine and Health (GIBH, http://english.gibh.cas.cn/about/at/) is focused  in  research  areas  including  stem  cell  and regenerative  medicine,  chemical  biology,  immunology  and  infectious  diseases.  Aimed  to achieve  the goal of "Healthy  China"  strategy  and satisfy  human  health demands,  GIBH is exploring disease mechanism with the cutting--edge  technologies and developing innovative protocols   for  disease   control   and  prevention.   It  provides   excellent   R&D  platform   in biomedicine and functions as an incubator for bioengineering and pharmaceutical industries to support local economic development as well as national strategic R&D programs. Reprogramming and Regeneration Laboratory

Pia  Cosmas  group  is  an  internationally  recognized  laboratory and will start at GIBH in August 2018. The group has as main objective to investigate the mechanisms controlling the reprogramming of somatic cells, and to determine if this reprogramming contributes to tissue regeneration in higher vertebrates. Cosmas  group  has  discovered  that  activation  of  the  Wnt/β--catenin  signalling  pathway enhances  cell--fusion--mediated  reprogramming  of  a  variety  of  somatic  cells  and  studied extensively  the  mechanism  behind  (Lluis  et  al.,  Cell  Stem  Cell  2008;  Stem  Cells  2010;  PNAS

2011; Aulicino  et al., Stem Cell Report 2014; Marucci  et al. Cell Reports  2014; De Jaime--‐ Soguero et al. Plos Genetics 2017). Cosmas group demonstrated  that regeneration  of the retina,  dopaminergic  neurons  in  Parkinsons  disease  and  of  liver  after  hepatectomy  is possible via Wnt controlled cell--fusion--mediated reprogramming (Sanges et al., Cell Reports

2013;  J.  of  Clinical  Investigation  2016;  Pesaresi  et  al.  eBioMedicine  2018;  Altarche--Xifro  et

al., eBioMedicine 2016; Pedone et al., Cell Reports 2017).  

In addition, Cosmas Group has a long interest in studying gene and chromatin function (Cantone et al, Cell 2009). Recently using super resolution microscopy (STORM), the group has  identified  a  new  model  of  chromatin  fiber  assembly  and  how  the  fiber  changes  in somatic and embryonic stem cells (Ricci et al. Cell 2015, Neguembor et al., NAR 2017).  

Post Description and Candidate requirements

The  Cosma  group  is  looking  for  a  highly  motivated  Research  Assistant  (RA)  with previous expertise in biology, biomedicine or related disciplines. The candidate will ideally hold a PhD and will have some previous experience in cell and molecular biology and preferentially in in cell culture. He/she will be a lab manager dedicated part of the time to administrative duties, including organization for the best functioning of the laboratory, and part of the time he/she will be a technical assistant for research projects. The candidate will have a very good knowledge of English.

Conditions

The  offer  is  to  cover  a  Research  Assistant  (RA)  position  with  a  competitive  salary  that

will be well matched relative to the cost of living in Guangzhou.

Starting Date

The job will start ideally as soon as the candidate is hired.

Application Procedure

All applications  must be addressed  to Pia Cosma;  and include  a full CV with contact details,  a  cover  motivation  letter  and  contacts  of  2--3  references.  Please  submit  your application at: pia.cosma@crg.eu

Deadline  July  31  2018  (note  that  applications  will  be  continually  monitored  and  suitable

candidates will be hired as soon as they are identified)

 

 

 

pls send your CV to pia.cosma@crg.eu

 


 

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