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中文论文题目: Expedient Construction of the Ziegler Intermediate Useful for the Synthesis of Forskolin via Consecutive Rearrangements
英文论文题目: Expedient Construction of the Ziegler Intermediate Useful for the Synthesis of Forskolin via Consecutive Rearrangements
作者: Heping Ye, Gang Deng, Jun Liu, and Fayang Qiu.
论文出处:
刊物名称: Organic Letters
年: 2009
卷: 11
期: 23
页: 5442-5444
联系作者: Fayang Qiu
收录类别:
影响因子: 5.128
摘要:

The Ziegler intermediate, useful for the total synthesis of forskolin, was synthesized in 10 reaction steps starting from commercially available α-ionone. This highly efficient synthesis relies on the success of two consecutive highly regio- and stereoselective rearrangements. The current synthesis has not only established an efficient synthetic route to access the Ziegler intermediate but it has also paved a way to the structural optimization of forskolin.

 
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