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专家人才

  • 姓名: 王涛
  • 性别: 男
  • 职称: 研究员
  • 学历: 博士
  • 电话: 
  • 传真: 
  • 电子邮件: wang_tao@gibh.ac.cn
  • 通讯地址 广州市科学城开源大道190号

    简历:

  • 2017.3-       Guangzhou Institutes of Biomedicine and Health    PI

    2015.4-2017.3 Yale University, Yale Stem Cell Center   Associated Research Scientist 

    2012.6-2015.4 The University of North Carolina-Chapel Hill, Postdoctoral Associate 

    2010.7-2012.6 Guangzhou Institutes of Biomedicine and health, Research Scientist 

    2006.9-2010.7 Guangzhou Institutes of Biomedicine and health, Research Scientist, Ph.D student

    2002.7-2005.9  NanKai University, Master Student 

    1998.7-2002.9 Yangtze University, Bachelor Student 

    研究领域:

  • We are interested in ageing biologyaging related diseases and stem cell regeneration. Cell aging (Cell Senescence) cause tissue dysfunction/degeneration. Cumulative researches uncovered distinct factors that can trigger senescence, such as telomere erosionDNA damagemitochondrial dysfunction and epigenetic alteration. One of our aims is to search for new proteins or factors maintaining genome integrity and stability, to this end, we perform whole genome wide screening and manipulate these factors to delay senescence even aging.

    Emerging reports suggested that elimination of senescent cell in mouse can delay aging or restore tissue function in some extent.  We are also exploiting vulnerabilities of senescent cell to identify novel pathways to selective killing of old cell.

    Organoids culture and stem cell differentiation provide powerful tools to investigate human disease mechanisms, we want to combine organoid culture and gene editing to model aging related diseases with purpose of invention of cure methods.

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