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专家人才

  • 姓名: 尹梦回
  • 性别: 男
  • 职称: 副研究员
  • 学历: 
  • 电话: 020-32015234
  • 传真: 
  • 电子邮件: yin_menghui@gibh.ac.cn
  • 通讯地址 广州萝岗区科学城开源大道190号

    简历:

  •   2001/09-2005/06 西南农业大学农学与生命科学学院 学士

      2005/09-2008/06 西南大学生物技术中心           硕士

      2008/09-2012/06 中国科学技术大学生命科学学院   博士

      2012/07-    中国科学院广州生物医药与健康研究院,化学与生物学所,助理研究员、副研究员

    研究领域:

  •   非编码RNA在肿瘤中的功能研究,RNARNA结合蛋白的相互作用在基因表达调控中的机理研究。

    承担科研项目情况:

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    社会任职:

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    获奖及荣誉:

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    代表论著:

  • 1.       Yin M# , Ren X# , Zhang X, Luo Y, Wang G, Huang K, Feng S, Bao X, Huang K, He X, Liang P, Wang Z, Tang H, He J*, Zhang B*. Selective killing of lung cancer cells by miRNA-506 molecule through inhibiting NF-κB p65 to evoke reactive oxygen species generation and p53 activation. Oncogene, , 2015, 34(6):691  

    2.       Xiaoshuai Ren, Menghui Yin, Xin Zhang, Zhe Wang, Shipeng Feng, Guoxin Wang,   Yingjun Luo, Peizhou Liang, Xiuqun Yang, Jianxing He* and Biliang Zhang*, Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells. Cancer Letters, 344(2),  195-203, 2014.

    3.       Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF1, Pei D, Wang H, Zhang B, Esteban MA. The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters. Cell Research. 2015. 25. 80-92.

    4.       Shipeng Feng, Shujie Cong, Xin Zhang, Xichen Bao, Wei Wang, Huiping Li, Zhe Wang, Guoxin Wang, Jianzhen Xu, Bowen Du, Dezhong Qu, Wei Xiong, Menghui Yin, Xiaoshuai Ren, Feifei Wang, Jianxing He and Biliang Zhang. MicroRNA-192 targeting retinoblastoma 1 (RB1) inhibits cell proliferation and induces cell apoptosis in lung cancer cells. Nucleic Acids Research 2011(39): Issue 15 Pp. 6669-6678.

    5.       Xiao YH, Yin MH, Hou L, Pei Y.Direct amplification of intron-containing hairpin RNA construct from genomic DNA. Biotechniques. 2006 Nov;41(5):548, 550, 552.

    6.       YH Xiao, MH Yin, L Hou, M Luo, Y Pei. Asymmetric overlap extension PCR method bypassing intermediate purification and the amplification of wild-type template in site-directed mutagenesis. Biotechnology Letters, Volume 29, Number 6: 925-930,2007